Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | GSK3B | P49841 | 1/20 | 0.66 |
| ▸ | PIM1 | P11309 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CDC25A | P30304 | 3/20 | 0.51 |
| ▸ | CDC25B | P30305 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250017 | 0.80 | GSK3B (1.00) | RAB9ANPC1HTTGSK3BPIM1 | |
| SCHEMBL1250019 | 0.80 | GSK3B (1.00) | RAB9ANPC1HTTGSK3BPIM1 | |
| SCHEMBL8085249 | 0.78 | PIM1 (0.67) | RAB9ANPC1HTTPIM1MAPT | |
| SCHEMBL15571574 | 0.78 | PIM1 (0.67) | RAB9ANPC1HTTPIM1MAPT | |
| SCHEMBL8085252 | 0.78 | PIM1 (0.67) | RAB9ANPC1HTTPIM1MAPT | |
| SCHEMBL8178919 | 0.77 | PIM1 (1.00) | RAB9ANPC1HTTGSK3BPIM1 | |
| SCHEMBL8176936 | 0.77 | PIM1 (1.00) | RAB9ANPC1HTTGSK3BPIM1 | |
| SCHEMBL10817032 | 0.73 | PIM1 (0.67) | RAB9ANPC1HTTPIM1MAPT | |
| SCHEMBL10805356 | 0.73 | PIM1 (0.67) | RAB9ANPC1HTTGSK3BPIM1 | |
| SCHEMBL10817027 | 0.73 | PIM1 (0.67) | RAB9ANPC1HTTPIM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286934-A1 | Use of Multi-Kinase Inhibitors to Treat RNA Virus Infections | ICAHN SCHOOL MED MOUNT SINAI (US) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286934-A1 | Use of Multi-Kinase Inhibitors to Treat RNA Virus Infections | EIF2AK2, SARS1, ACE2 | RAB9A 1744/4885NPC1 1643/4885HTT 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.