Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25414303 | 1.00 | RAB9A (0.64) | RAB9AKDM4CPOLBHPGDLTA4H | |
| SCHEMBL19198550 | 0.84 | RAB9A (0.69) | RAB9APOLBLTA4HLMNAGAA | |
| SCHEMBL19223057 | 0.83 | PPARG (0.60) | RAB9AKDM4CLTA4HF2PRSS1 | |
| SCHEMBL10054992 | 0.83 | RAB9A (0.83) | RAB9ALTA4HALDH1A1PDE4BKMT2A | |
| SCHEMBL19198137 | 0.79 | RAB9A (0.63) | RAB9AKDM4CLTA4HF2LMNA | |
| SCHEMBL30520217 | 0.79 | RAB9A (0.63) | RAB9AKDM4CLTA4HF2LMNA | |
| SCHEMBL19198628 | 0.79 | RAB9A (1.00) | RAB9APOLBHPGDLTA4HGAA | |
| SCHEMBL4805011 | 0.76 | LTA4H (0.79) | RAB9AHPGDLTA4HALDH1A1KMT2A | |
| SCHEMBL11080159 | 0.76 | RAB9A (0.58) | RAB9APOLBLTA4HF2SMN1; SMN2 | |
| SCHEMBL11078808 | 0.76 | SMN1; SMN2 (0.60) | RAB9APOLBLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM5A, KDM1A | RAB9A 3032/4885KDM4C 18/4885POLB 2023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.