Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.49 |
| ▸ | TDO2 | P48775 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 8/20 | 0.43 |
| ▸ | GSTM2 | P28161 | 8/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31054075 | 0.87 | IDO1 (0.46) | IDO1MEN1KMT2AGSTP1GSTM2 | |
| SCHEMBL31053997 | 0.84 | IDO1 (0.45) | IDO1TDO2MEN1KMT2AGSTP1 | |
| SCHEMBL31054006 | 0.81 | GSTP1 (0.53) | IDO1TDO2MEN1KMT2AGSTP1 | |
| SCHEMBL31054063 | 0.81 | MEN1 (0.53) | IDO1TDO2MEN1KMT2AGSTP1 | |
| SCHEMBL25343517 | 0.80 | IDO1 (0.49) | IDO1TDO2MEN1KMT2AGSTP1 | |
| SCHEMBL25342570 | 0.79 | MEN1 (0.44) | IDO1TDO2MEN1KMT2AGSTP1 | |
| SCHEMBL25342264 | 0.78 | IDO1 (0.47) | IDO1TDO2MEN1KMT2AGSTP1 | |
| SCHEMBL31054034 | 0.75 | MEN1 (0.46) | IDO1TDO2MEN1KMT2AGSTP1 | |
| SCHEMBL25341098 | 0.73 | POLB (0.47) | IDO1TDO2MEN1KMT2AGSTP1 | |
| SCHEMBL31053971 | 0.72 | MEN1 (0.55) | IDO1TDO2MEN1KMT2AGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574822-A | Novel PROTAC compounds | 甘李药业股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023143494-A1 | NEW PROTAC COMPOUND | 甘李药业股份有限公司 | 2023-08-03 | — | — | WO | disclosed |