Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 5/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30520877 | 0.86 | ALDH1A1 (0.39) | POLBIDO1TDO2ALDH1A1HPGD | |
| SCHEMBL30521137 | 0.85 | ACHE (0.38) | POLBIDO1TDO2ALDH1A1HPGD | |
| SCHEMBL25341745 | 0.85 | ACHE (0.38) | POLBIDO1TDO2ALDH1A1HPGD | |
| SCHEMBL31053925 | 0.81 | POLB (0.44) | POLBHDAC3HDAC1HDAC11HDAC8 | |
| SCHEMBL25343022 | 0.81 | ACHE (0.37) | POLBIDO1TDO2ALDH1A1HPGD | |
| SCHEMBL25341816 | 0.74 | ALDH1A1 (0.35) | POLBHDAC1HDAC8HDAC6MYC | |
| SCHEMBL30520827 | 0.73 | POLB (0.37) | POLBHDAC3HDAC1HDAC11HDAC8 | |
| SCHEMBL25342017 | 0.73 | POLB (0.37) | POLBHDAC3HDAC1HDAC11HDAC8 | |
| SCHEMBL30521247 | 0.73 | IDO1 (0.49) | IDO1TDO2MEN1KMT2AGSTP1 | |
| SCHEMBL25342122 | 0.72 | POLB (0.36) | POLBMYCIDO1TDO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143494-A1 | NEW PROTAC COMPOUND | 甘李药业股份有限公司 | 2023-08-03 | — | — | WO | disclosed |