Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.49 |
| ▸ | TDO2 | P48775 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 7/20 | 0.40 |
| ▸ | GSTM2 | P28161 | 7/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25342264 | 0.86 | IDO1 (0.47) | IDO1TDO2MEN1KMT2AKCNH2 | |
| SCHEMBL31054006 | 0.80 | GSTP1 (0.53) | IDO1TDO2MEN1KMT2AKCNH2 | |
| SCHEMBL25342570 | 0.80 | MEN1 (0.44) | IDO1TDO2MEN1KMT2AKCNH2 | |
| SCHEMBL30521247 | 0.80 | IDO1 (0.49) | IDO1TDO2MEN1KMT2AKCNH2 | |
| SCHEMBL30521257 | 0.77 | KCNH2 (0.41) | IDO1TDO2MEN1KMT2AKCNH2 | |
| SCHEMBL1076589 | 0.74 | MEN1 (0.60) | IDO1MEN1KMT2AKCNH2GSTP1 | |
| SCHEMBL7463890 | 0.73 | NSD2 (0.62) | IDO1MEN1KMT2AKCNH2GSTP1 | |
| SCHEMBL7467184 | 0.73 | MEN1 (0.56) | IDO1MEN1KMT2AKCNH2GSTP1 | |
| SCHEMBL3505281 | 0.73 | MEN1 (0.59) | IDO1MEN1KMT2AKCNH2GSTP1 | |
| SCHEMBL12427044 | 0.73 | MEN1 (0.47) | IDO1TDO2MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143494-A1 | NEW PROTAC COMPOUND | 甘李药业股份有限公司 | 2023-08-03 | — | — | WO | disclosed |