Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25300597 | 0.89 | IMPDH2 (0.56) | IMPDH2IMPDH1CYP17A1AAK1CYP1A2 | |
| SCHEMBL30522600 | 0.89 | IMPDH2 (0.56) | IMPDH2IMPDH1CYP17A1AAK1CYP1A2 | |
| SCHEMBL527200 | 0.88 | IMPDH2 (0.46) | IMPDH2IMPDH1CYP17A1CYP1A2NTRK1 | |
| SCHEMBL30522521 | 0.83 | KIT (0.51) | IMPDH2IMPDH1CYP17A1AAK1CYP1A2 | |
| SCHEMBL25255296 | 0.83 | KIT (0.51) | IMPDH2IMPDH1CYP17A1AAK1CYP1A2 | |
| SCHEMBL10272835 | 0.81 | CYP17A1 (0.58) | IMPDH2IMPDH1CYP17A1CYP1A2NTRK1 | |
| SCHEMBL12934590 | 0.79 | CYP1A2 (0.49) | CYP17A1AAK1CYP1A2METAP2POLQ | |
| SCHEMBL527609 | 0.78 | ABL1 (0.45) | CYP17A1CYP1A2MAPTALDH1A1KDM4E | |
| SCHEMBL10272836 | 0.78 | IMPDH2 (0.55) | IMPDH2IMPDH1CYP17A1CYP1A2NTRK1 | |
| SCHEMBL25252432 | 0.77 | NTRK1 (0.48) | IMPDH2IMPDH1AAK1CYP1A2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |