Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.53 |
| ▸ | HPGD | P15428 | 9/20 | 0.53 |
| ▸ | GLA | P06280 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 10/20 | 0.49 |
| ▸ | GAA | P10253 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156623 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL17950071 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL22448220 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL14315159 | 0.75 | RAB9A (0.57) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL3156629 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL23090057 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL8811701 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL16346664 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL9298339 | 0.73 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL1901476 | 0.72 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11730810-B2 | Composition comprising an antigen and a substituted imidazo[1,2-a]pyrimidine for enhancing human immune response | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11730810-B2 | Composition comprising an antigen and a substituted imidazo[1,2-a]pyrimidine for enhancing human immune response | CD4, MYD88, STING1 | ALDH1A1 2611/4885KDM4E 3625/4885HPGD 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.