SCHEMBL30523218

SCHEMBL30523218

COc1ccc(C(C)C2(O)CCCCC2N(C)C)cc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 11/20 0.46
SLC6A3 Q01959 10/20 0.46
SLC6A2 P23975 8/20 0.46
LMNA P02545 1/20 0.46
CNR1 P21554 1/20 0.46
HTR2A P28223 1/20 0.46
HRH1 P35367 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD11B1 P28845 1/20 0.37
SLC22A1 O15245 1/20 0.36
OPRM1 P35372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7704043 0.84 SLC6A4 (0.45) SLC6A4SLC6A3SLC6A2LMNACNR1
SCHEMBL639268 0.72 SLC6A4 (0.60) SLC6A4SLC6A3SLC6A2LMNACNR1
Hydrochloric Acid SCHEMBL5798391 0.69 TSHR (0.46) SLC6A4SLC6A3SLC6A2LMNACNR1
SCHEMBL11837340 0.68 SLC6A4 (0.49) SLC6A4SLC6A3SLC6A2LMNACNR1
Hydrochloric Acid SCHEMBL11835693 0.68 SLC6A4 (0.50) SLC6A4SLC6A3SLC6A2LMNACNR1
SCHEMBL17296892 0.67 ATM (0.47) SLC6A4SLC6A3SLC6A2LMNACNR1
SCHEMBL4645586 0.67 SLC6A2 (0.39) SLC6A4SLC6A3SLC6A2LMNACNR1
SCHEMBL12026858 0.66 SLC6A2 (0.63) SLC6A4SLC6A3SLC6A2LMNACNR1
SCHEMBL10616044 0.66 SLC6A4 (0.59) SLC6A4SLC6A3SLC6A2LMNACNR1
SCHEMBL11836977 0.66 SLC6A4 (0.39) SLC6A4SLC6A3SLC6A2LMNACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3580198-B1 A PROCESS FOR PREPARATION OF1-[2-(DIMETHYLAMINO)-1-(4-HYDROXYPHENYL) ETHYL]-CYCLOHEXANOL AND SALTS THEREOF R L FINECHEM PRIVATE LTD (IN) 2023-08-09 EP claimed