Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523218 | 0.84 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL9023079 | 0.78 | L3MBTL1 (0.38) | LMNA | |
| SCHEMBL639268 | 0.74 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL27651524 | 0.74 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2MAOBMAOA | |
| SCHEMBL11836977 | 0.70 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL11837340 | 0.70 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| Hydrochloric Acid SCHEMBL11835693 | 0.69 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL30523217 | 0.69 | SLC6A4 (0.37) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL11834256 | 0.69 | GAA (0.39) | SLC6A4SLC6A3LMNAALDH1A1MEN1 | |
| SCHEMBL6457544 | 0.69 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165487-A1 | DERIVATIVES OF VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME | Sepracor Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059851-A1 | DERIVATIVES OF VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME | SEPRACOR INC. (US) | 2000-10-12 | — | — | WO | disclosed |