Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643005 | 0.79 | ITGA4 (0.40) | ALDH1A1 | |
| SCHEMBL13637842 | 0.77 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL4510516 | 0.77 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL11834256 | 0.71 | GAA (0.39) | SLC6A4SLC6A3LMNAALDH1A1MAPK1 | |
| SCHEMBL17296892 | 0.70 | ATM (0.47) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL7704043 | 0.69 | SLC6A4 (0.45) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL1566474 | 0.68 | ALOX5 (0.51) | SLC6A2SLC6A4SLC6A3ALDH1A1MMP1 | |
| SCHEMBL11848170 | 0.68 | MME (0.40) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL10616814 | 0.67 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL3952145 | 0.67 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957470-A1 | PROCESS FOR SELECTIVE SYNTHESIS OF ENANTIOMERS OF SUBSTITUTED 1-(2-AMINO-1-PHENYL-ETHYL)-CYCLOHEXANOLS | Wyeth (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007067501-A1 | PROCESS FOR SELECTIVE SYNTHESIS OF ENANTIOMERS OF SUBSTITUTED 1-(2-AMINO-1-PHENYL-ETHYL)-CYCLOHEXANOLS | WYETH (US) | 2007-06-14 | — | — | WO | disclosed |