Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22361713 | 1.00 | MEN1 (0.44) | MEN1KMT2ACXCR3BCHEACHE | |
| SCHEMBL20778607 | 0.89 | CXCR3 (0.42) | MEN1KMT2ACXCR3BCHEACHE | |
| SCHEMBL20766411 | 0.88 | MEN1 (0.46) | MEN1KMT2ACXCR3BCHEACHE | |
| SCHEMBL30523669 | 0.88 | MEN1 (0.46) | MEN1KMT2ACXCR3BCHEACHE | |
| SCHEMBL22361741 | 0.81 | OPRL1 (0.47) | MEN1KMT2ABCHEACHEBACE1 | |
| SCHEMBL30523686 | 0.81 | OPRL1 (0.47) | MEN1KMT2ABCHEACHEBACE1 | |
| SCHEMBL12074561 | 0.80 | ACHE (0.50) | MEN1KMT2ACXCR3BCHEACHE | |
| SCHEMBL20767067 | 0.79 | CXCR3 (0.65) | MEN1KMT2ACXCR3BCHEACHE | |
| SCHEMBL20766753 | 0.78 | BCHE (0.64) | MEN1KMT2ACXCR3BCHEACHE | |
| SCHEMBL29546328 | 0.78 | BCHE (0.64) | MEN1KMT2ACXCR3BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466803-A | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-111132976-B | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2023-08-22 | — | — | CN | disclosed |