Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17490462 | 1.00 | L3MBTL1 (0.49) | L3MBTL1RPS6KA5CCNCCDK8PKM | |
| SCHEMBL29174646 | 0.90 | CCNC (0.49) | RPS6KA5CCNCCDK8PKMHTR6 | |
| SCHEMBL30725457 | 0.90 | CCNC (0.49) | RPS6KA5CCNCCDK8PKMHTR6 | |
| SCHEMBL31006842 | 0.86 | ABL1 (0.41) | L3MBTL1HSD11B1ABL1BCRBRD4 | |
| SCHEMBL31006838 | 0.82 | BRD4 (0.38) | L3MBTL1HSD11B1ABL1BCRBRD4 | |
| SCHEMBL29394672 | 0.79 | HSD11B1 (0.40) | L3MBTL1HSD11B1ABL1BCRHTR6 | |
| SCHEMBL18662641 | 0.79 | HSD11B1 (0.40) | L3MBTL1HSD11B1ABL1BCRHTR6 | |
| SCHEMBL30546670 | 0.79 | RPS6KA5 (0.47) | RPS6KA5 | |
| SCHEMBL18979242 | 0.79 | RPS6KA5 (0.47) | RPS6KA5 | |
| SCHEMBL1779514 | 0.78 | L3MBTL1 (0.60) | L3MBTL1PKMHSD11B1PTGDR2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480029-A | 2-Aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |