SCHEMBL30524186

SCHEMBL30524186

N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DPP3 Q9NY33 5/20 0.61
▸ OPRM1 P35372 4/20 0.56
▸ OPRD1 P41143 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30659496 0.97 DPP3 (0.64) DPP3OPRM1OPRD1
SCHEMBL29772686 0.93 DPP3 (0.65) DPP3OPRM1
SCHEMBL29577213 0.93 DPP3 (0.65) DPP3OPRM1
SCHEMBL30050936 0.92 DPP3 (0.69) DPP3OPRM1
SCHEMBL29974089 0.92 DPP3 (0.66) DPP3OPRM1OPRD1
SCHEMBL30292652 0.91 OPRM1 (0.62) DPP3OPRM1OPRD1
SCHEMBL29842186 0.90 DPP3 (0.65) DPP3
SCHEMBL30424046 0.90 DPP3 (0.67) DPP3OPRM1
SCHEMBL20749886 0.89 OPRM1 (0.63) DPP3OPRM1
SCHEMBL14242750 0.89 OPRM1 (0.63) DPP3OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250027090-A1 MIRROR-IMAGE SELECTION OF L-NUCLEIC ACID APTAMERS TSINGHUA UNIVERSITY (CN) 2025-01-23 — — US disclosed
EP-4473115-A1 MIRROR-IMAGE SELECTION OF L-NUCLEIC ACID APTAMERS Tsinghua University (CN) 2024-12-11 — — EP disclosed
WO-2024097829-A1 APTAMER-DIRECT INHIBITOR CONJUGATES AND METHODS OF USING THE SAME DUKE UNIVERSITY (US) 2024-05-10 — — WO disclosed
US-20230340501-A1 COORDINATED COEXPRESSION OF THROMBIN ABSCI CORP (US) 2023-10-26 — — US disclosed
WO-2023148646-A1 MIRROR-IMAGE SELECTION OF L-NUCLEIC ACID APTAMERS TSINGHUA UNIVERSITY (CN) 2023-08-10 — — WO disclosed
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