Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29577213 | 1.00 | DPP3 (0.65) | DPP3OPRM1SLC6A2 | |
| SCHEMBL30610091 | 0.96 | DPP3 (0.69) | DPP3OPRM1 | |
| SCHEMBL29648960 | 0.96 | DPP3 (0.69) | DPP3OPRM1 | |
| SCHEMBL30659496 | 0.95 | DPP3 (0.64) | DPP3OPRM1 | |
| Endomorphin-1 SCHEMBL21811384 | 0.95 | — | — | |
| Endomorphin-1 SCHEMBL29577928 | 0.95 | — | — | |
| Endomorphin-1 SCHEMBL29379764 | 0.95 | — | — | |
| SCHEMBL20749886 | 0.95 | OPRM1 (0.63) | DPP3OPRM1SLC6A2 | |
| Endomorphin-1 SCHEMBL29390342 | 0.95 | — | — | |
| SCHEMBL14242750 | 0.95 | OPRM1 (0.63) | DPP3OPRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109936-A1 | NOVEL MACROCYCLIC OPIOID PEPTIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| WO-2022150167-A2 | NOVEL MACROCYCLIC OPIOID PEPTIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109936-A1 | NOVEL MACROCYCLIC OPIOID PEPTIDES | OPRL1, OPRM1, OPRK1 | DPP3 673/4885OPRM1 2/4885SLC6A2 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.