Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005868 | 1.00 | LMNA (0.68) | LMNAL3MBTL1MAPTMEN1KMT2A | |
| Ether SCHEMBL2009992 | 0.88 | L3MBTL1 (0.54) | LMNAL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL12572410 | 0.87 | HTT (0.50) | LMNAL3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL28593997 | 0.79 | LMNA (0.61) | LMNAL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL423891 | 0.77 | L3MBTL1 (0.71) | LMNAL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL8273082 | 0.76 | L3MBTL1 (0.56) | LMNAL3MBTL1MAPTKMT2AKDM4E | |
| SCHEMBL28168224 | 0.75 | MAOB (0.53) | L3MBTL1MAPTKMT2AKDM4ERAB9A | |
| SCHEMBL7805490 | 0.75 | KMT2A (0.53) | LMNAL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL3306870 | 0.74 | PDE2A (0.50) | LMNAL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL28681600 | 0.74 | PDE2A (0.44) | LMNAL3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854630-B | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-116854630-A | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-112055712-B | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2023-07-14 | — | — | CN | disclosed |