Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525040 | 0.88 | RHOA (0.39) | TSHRHPGDALOX15RHOAMAPT | |
| SCHEMBL20791009 | 0.88 | RHOA (0.39) | TSHRHPGDALOX15RHOAMAPT | |
| SCHEMBL20790760 | 0.88 | RHOA (0.39) | TSHRHPGDALOX15RHOAMAPT | |
| SCHEMBL29232682 | 0.82 | LMNA (0.43) | TSHRRHOAKDM4EKMT2ALMNA | |
| SCHEMBL29232683 | 0.82 | LMNA (0.43) | TSHRRHOAKDM4EKMT2ALMNA | |
| SCHEMBL29453091 | 0.82 | LMNA (0.43) | TSHRRHOAKDM4EKMT2ALMNA | |
| SCHEMBL30524832 | 0.80 | SLC9A1 (0.42) | TSHRLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL26398066 | 0.71 | RHOA (0.35) | RHOAMAPTADCY1HTR1ALMNA | |
| SCHEMBL1397499 | 0.70 | PARP1 (0.57) | TSHRHPGDALOX15MAPTKDM4E | |
| SCHEMBL20826107 | 0.69 | HPGD (0.62) | TSHRHPGDRHOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601798-B | Bisamide sarcomere activating compounds and uses thereof | 美国安进公司 | 2023-08-11 | — | — | CN | disclosed |