Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 2/20 | 0.55 |
| ▸ | F3 | P13726 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TOP1 | P11387 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120269 | 0.91 | FAAH (0.67) | F7F3FAAHTERTPTPN1 | |
| SCHEMBL30528374 | 0.91 | FAAH (0.50) | F7F3FAAHTERTPTPN1 | |
| SCHEMBL1219787 | 0.91 | F7 (0.67) | F7F3FAAHTERTPTPN1 | |
| SCHEMBL1219790 | 0.91 | F7 (0.67) | F7F3FAAHTERTPTPN1 | |
| SCHEMBL1219842 | 0.89 | F7 (0.70) | F7F3FAAHTERTPTPN1 | |
| SCHEMBL28426444 | 0.89 | ALDH1A1 (0.50) | F7F3FAAHTERTPTPN1 | |
| SCHEMBL1219841 | 0.89 | F7 (0.70) | F7F3FAAHTERTPTPN1 | |
| SCHEMBL811442 | 0.87 | FAAH (0.72) | F7F3FAAHTERTPTPN1 | |
| SCHEMBL14244808 | 0.87 | FAAH (0.72) | F7F3FAAHTERTPTPN1 | |
| SCHEMBL432635 | 0.87 | FAAH (0.72) | F7F3FAAHTERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600803-A | Macrocyclic urea orexin receptor agonists | 默沙东有限责任公司 | 2023-08-15 | — | — | CN | claimed |
| CN-116600803-A | Macrocyclic urea orexin receptor agonists | 默沙东有限责任公司 | 2023-08-15 | — | — | CN | disclosed |