Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30528212 | 0.71 | KDM4E (0.46) | MAPTALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28581650 | 0.71 | KDM4E (0.46) | MAPTALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL30528214 | 0.70 | KDM4E (0.40) | MAPTALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28588152 | 0.67 | KDM4E (0.51) | MAPTALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28587261 | 0.64 | KDM4E (0.53) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL28584206 | 0.63 | KDM4E (0.54) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL17324966 | 0.62 | FAAH (0.53) | MAPTALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL10576996 | 0.62 | MAPT (0.43) | MAPTALDH1A1LMNABRD4SMARCA2 | |
| SCHEMBL23544879 | 0.60 | MAPT (0.49) | MAPTALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL30564180 | 0.60 | KDM4E (0.57) | ALDH1A1LMNAKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824396-B | Acrylic ketone derivative of N-acetyl lomefloxacin and preparation method and application thereof | 河南大学 | 2023-08-11 | — | — | CN | disclosed |