Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943410 | 1.00 | TSHR (0.52) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL16489316 | 1.00 | TSHR (0.52) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL20767532 | 0.98 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL30593797 | 0.98 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL27210237 | 0.92 | TSHR (0.56) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL494822 | 0.85 | TSHR (0.52) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL495446 | 0.85 | TSHR (0.52) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL494661 | 0.85 | TSHR (0.52) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL494385 | 0.85 | TSHR (0.52) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL494833 | 0.85 | TSHR (0.52) | TSHRL3MBTL1LMNAALDH1A1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180156810-A1 | FLUORESCENT COMPOUNDS | BIOTIUM, INC. | 2018-06-07 | — | — | US | disclosed |
| US-9791450-B2 | Fluorescent compounds | BIOTIUM, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| EP-2223086-B2 | FLUORESCENT COMPOUNDS - LABELING DYES | BIOTIUM INC (US) | 2016-06-01 | — | — | EP | disclosed |
| US-20160033520-A1 | FLUORESCENT COMPOUNDS | BIOTIUM, INC. | 2016-02-04 | — | — | US | disclosed |
| US-20150330973-A1 | Kits for analysis of biological samples | ANASPEC INCORPORATED (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150330973-A1 | Kits for analysis of biological samples | ANASPEC INCORPORATED (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150330973-A1 | Kits for analysis of biological samples | ANASPEC INCORPORATED (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150259535-A1 | Fluorescent dyes | ANASPEC INC (US) | 2015-09-17 | — | — | US | disclosed |
| US-20150259535-A1 | Fluorescent dyes | ANASPEC INC (US) | 2015-09-17 | — | — | US | disclosed |
| US-20150259535-A1 | Fluorescent dyes | ANASPEC INC (US) | 2015-09-17 | — | — | US | disclosed |
| WO-2009078970-A1 | FLUORESCENT COMPOUNDS | BIOTIUM, INC. (US) | 2009-06-25 | — | — | WO | disclosed |
| US-20090156799-A1 | Methods of making dyes | DIWU ZHENJUN | 2009-06-18 | — | — | US | disclosed |
| US-20090156799-A1 | Methods of making dyes | DIWU ZHENJUN | 2009-06-18 | — | — | US | disclosed |
| US-20090156799-A1 | Methods of making dyes | DIWU ZHENJUN | 2009-06-18 | — | — | US | disclosed |
| US-7465810-B2 | Chemically reactive carbocyanine dyes that are intramolecularly connected or crosslinked between the 1-position and 3'-position by a polyamino acid linker; reduction of the ground state aggregation caused by steric hindrance of the crosslinking results in more fluorescent on proteins and nucleic acids | ANASPEC, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7465810-B2 | Chemically reactive carbocyanine dyes that are intramolecularly connected or crosslinked between the 1-position and 3'-position by a polyamino acid linker; reduction of the ground state aggregation caused by steric hindrance of the crosslinking results in more fluorescent on proteins and nucleic acids | ANASPEC, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7465810-B2 | Chemically reactive carbocyanine dyes that are intramolecularly connected or crosslinked between the 1-position and 3'-position by a polyamino acid linker; reduction of the ground state aggregation caused by steric hindrance of the crosslinking results in more fluorescent on proteins and nucleic acids | ANASPEC, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| WO-2008127139-A1 | INDICYANINE DYES AND THE DERIVATIVES THEREOF FOR ANALYSING BIOLOGICAL MICROMOLECULES | INSTITUT MOLEKULYARNOI BIOLOGII IM. V.A. ENGELDARDTA ROSSIISKOI AKADEMII NAUK (RU) | 2008-10-23 | — | — | WO | disclosed |
| US-20060121503-A1 | Chemically reactive carbocyanine dyes that are intramolecularly connected or crosslinked between the 1-position and 3'-position by a polyamino acid linker; reduction of the ground state aggregation caused by steric hindrance of the crosslinking results in more fluorescent on proteins and nucleic acids | ANASPEC, INC. | 2006-06-08 | — | — | US | disclosed |
| WO-2006047452-A2 | REACTIVE 1,3’-CROSSLINKED CARBOCYANINES AND THEIR BIOCONJUGATES | ANASPEC, INC. (US) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060121503-A1 | Chemically reactive carbocyanine dyes that are intramolecularly connected or crosslinked between the 1-position and 3'-position by a polyamino acid linker; reduction of the ground state aggregation caused by steric hindrance of the crosslinking results in more fluorescent on proteins and nucleic acids | LIG1, LIG4, LIG3 | TSHR 4019/4885L3MBTL1 264/4885LMNA 807/4885 |
| US-20090156799-A1 | Methods of making dyes | CBR3, CBR1, GLO1 | TSHR 4331/4885L3MBTL1 912/4885LMNA 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.