Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 9/20 | 0.36 |
| ▸ | ATP1B1 | P05026 | 9/20 | 0.36 |
| ▸ | ATP1A3 | P13637 | 9/20 | 0.36 |
| ▸ | ATP1B2 | P14415 | 9/20 | 0.36 |
| ▸ | ATP1A2 | P50993 | 9/20 | 0.36 |
| ▸ | ATP1B3 | P54709 | 9/20 | 0.36 |
| ▸ | FXYD2 | P54710 | 9/20 | 0.36 |
| ▸ | ATP1A4 | Q13733 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17310996 | 0.88 | ATP1A1 (0.31) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Hydrochloric Acid SCHEMBL17311121 | 0.86 | ATP1A1 (0.30) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL10089209 | 0.79 | ATP1A1 (0.33) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL11810987 | 0.78 | ALDH1A1 (0.32) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL27651849 | 0.75 | — | — | |
| SCHEMBL9584454 | 0.72 | ALDH1A1 (0.35) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL22209073 | 0.70 | ALDH1A1 (0.42) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL8922242 | 0.67 | ATP1A1 (0.39) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL9840935 | 0.67 | ALDH1A1 (0.33) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL17310987 | 0.67 | CYP1A2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143322-A1 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT PATENT & LICENCE TRADING LTD., C/O THE B-NET (GB) | 2010-06-10 | — | — | US | claimed |
| EP-1917006-A2 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT Patent & Licence Trading Ltd. (GB) | 2008-05-07 | — | — | EP | claimed |
| WO-2006136454-A2 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT PATENT & LICENCE TRADING LTD. (GB) | 2006-12-28 | — | — | WO | claimed |
| US-20100143322-A1 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT PATENT & LICENCE TRADING LTD., C/O THE B-NET (GB) | 2010-06-10 | — | — | US | disclosed |
| EP-1917006-A2 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT Patent & Licence Trading Ltd. (GB) | 2008-05-07 | — | — | EP | disclosed |
| WO-2006136454-A2 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT PATENT & LICENCE TRADING LTD. (GB) | 2006-12-28 | — | — | WO | disclosed |