Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 8/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | MDH2 | P40926 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3048710 | 0.91 | HSD17B10 (0.50) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL3040959 | 0.87 | HSD17B10 (0.46) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| Hydrochloric Acid SCHEMBL3050165 | 0.81 | CHEK1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| Hydrochloric Acid SCHEMBL3046777 | 0.80 | CHEK1 (0.52) | POLBSMN1; SMN2CHEK1 | |
| SCHEMBL3837432 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| Hydrochloric Acid SCHEMBL3044154 | 0.74 | CHEK1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10CHEK1 | |
| Hydrochloric Acid SCHEMBL3033516 | 0.74 | CHEK1 (0.50) | CHEK1 | |
| Hydrochloric Acid SCHEMBL3044456 | 0.72 | CHEK1 (0.44) | CHEK1 | |
| Hydrochloric Acid SCHEMBL3043804 | 0.72 | CHEK1 (0.44) | CHEK1 | |
| SCHEMBL3049431 | 0.72 | CHEK1 (0.44) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745641-B2 | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20090054407-A1 | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054407-A1 | Nitrogen-containing heterocyclic compound | NR4A1, NR5A2, PRMT8 | ALDH1A1 3131/4885KDM4E 488/4885HPGD 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.