Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.47 |
| ▸ | CDK9 | P50750 | 5/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.47 |
| ▸ | CLK1 | P49759 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400152 | 0.84 | DYRK1A (0.49) | DYRK1ACDK9DYRK1BDYRK2CLK1 | |
| SCHEMBL626362 | 0.81 | DYRK1A (0.49) | DYRK1ACDK9DYRK1BDYRK2CLK1 | |
| SCHEMBL8574385 | 0.80 | DHODH (0.49) | DYRK1ACDK9DYRK1BDYRK2CLK1 | |
| Water SCHEMBL25347465 | 0.80 | DYRK1A (0.48) | DYRK1ACDK9DYRK1BDYRK2CLK1 | |
| SCHEMBL10416744 | 0.75 | DHODH (0.50) | DYRK1ACDK9DYRK1BDYRK2CLK1 | |
| SCHEMBL891835 | 0.72 | ALDH1A1 (0.52) | DYRK1ACDK9DYRK1BDYRK2CLK1 | |
| SCHEMBL30583760 | 0.72 | ALDH1A1 (0.52) | DYRK1ACDK9DYRK1BDYRK2CLK1 | |
| SCHEMBL29012657 | 0.70 | ALDH1A1 (0.48) | DYRK1ACDK9DYRK1BDYRK2CLK1 | |
| SCHEMBL9768818 | 0.69 | DHODH (0.47) | DYRK1ACDK9DYRK1BDYRK2CLK1 | |
| SCHEMBL7524860 | 0.69 | KDM4E (0.44) | DYRK1ACDK9DYRK1BDYRK2CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606321-A | Compound with chloroiodohydroxyquinoline tetravalent platinum structure, preparation method and application thereof | 聊城大学 | 2023-08-18 | — | — | CN | disclosed |