Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25268511 | 1.00 | GRM6 (0.33) | GRM6GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL25275778 | 0.89 | PKM (0.32) | MAPT | |
| SCHEMBL25220796 | 0.89 | PKM (0.32) | MAPT | |
| SCHEMBL25279111 | 0.89 | IL1B (0.33) | MEN1KMT2A | |
| SCHEMBL30464446 | 0.89 | IL1B (0.33) | MEN1KMT2A | |
| SCHEMBL25222644 | 0.89 | IL1B (0.33) | MEN1KMT2A | |
| SCHEMBL25285585 | 0.88 | CHRM4 (0.34) | MAPTTDP1MEN1KMT2A | |
| SCHEMBL25279915 | 0.88 | CHRM4 (0.34) | MAPTTDP1MEN1KMT2A | |
| SCHEMBL25218322 | 0.88 | CHRM4 (0.34) | MAPTTDP1MEN1KMT2A | |
| SCHEMBL25263303 | 0.86 | SERPINE1 (0.36) | MAPTCYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102184-A1 | BICYCLIC AMINE COMPOUNDS AS CDK12 INHIBITORS | INCYTE CORPORATION (US) | 2023-06-08 | — | — | WO | disclosed |