Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CPT1A | P50416 | 2/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | WDR5 | P61964 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25351103 | 1.00 | MEN1 (0.45) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL30535443 | 0.89 | MEN1 (0.50) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL25351564 | 0.89 | MEN1 (0.50) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL31561130 | 0.85 | CPT1A (0.44) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL25350572 | 0.85 | ALDH1A1 (0.47) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL25367459 | 0.84 | ALDH1A1 (0.51) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL30544027 | 0.84 | ALDH1A1 (0.51) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL25351576 | 0.82 | MEN1 (0.51) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL25351018 | 0.81 | MEN1 (0.44) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL30535715 | 0.81 | MEN1 (0.44) | MEN1KMT2AHTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479138-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | Accent Therapeutics, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023154519-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |