Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.87 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.87 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.87 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.87 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.87 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.87 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.87 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.87 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.87 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.87 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.87 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.87 |
| ▸ | EGFR | P00533 | 2/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.87 |
| ▸ | BRD4 | O60885 | 1/20 | 0.87 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.87 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.87 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.87 |
| ▸ | LTA4H | P09960 | 1/20 | 0.87 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vorinostat SCHEMBL9018 | 0.93 | HDAC1 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL19754407 | 0.93 | HDAC1 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL23055010 | 0.93 | HDAC1 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL8261596 | 0.93 | HDAC1 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL18660195 | 0.92 | MAPT (0.74) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL23055007 | 0.92 | HDAC1 (0.96) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| Vorinostat SCHEMBL28095919 | 0.89 | HDAC1 (0.90) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL12659217 | 0.88 | HDAC1 (0.89) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL31635263 | 0.88 | HDAC1 (0.83) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL8226957 | 0.87 | HDAC1 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11788145-B2 | Epigeneiic silencing of NMT2 | PACYLEX PHARMACEUTICALS INC. (CA) | 2023-10-17 | — | — | US | disclosed |
| EP-3325662-B1 | EPIGENETIC SILENCING OF NMT2 | PACYLEX PHARMACEUTICALS INC (CA) | 2023-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11788145-B2 | Epigeneiic silencing of NMT2 | NNMT, NMT2, NMT1 | HDAC6 348/4885HDAC1 157/4885HDAC3 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.