⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15689755 | 0.81 | — | — | |
| SCHEMBL5764417 | 0.77 | — | — | |
| SCHEMBL7054842 | 0.77 | — | — | |
| SCHEMBL5424411 | 0.77 | ALDH1A1 (0.50) | — | |
| SCHEMBL248143 | 0.77 | ALDH1A1 (0.50) | — | |
| SCHEMBL2257580 | 0.75 | BLM (0.47) | — | |
| SCHEMBL1291029 | 0.74 | — | — | |
| SCHEMBL11695076 | 0.74 | — | — | |
| SCHEMBL16996650 | 0.74 | MMP1 (0.48) | — | |
| SCHEMBL112862 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 792 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112624969-A | Quinoline derivative, preparation method thereof and application thereof in preventing and treating plant viruses and killing bacteria | 南开大学 | 2021-04-09 | — | — | CN | claimed |
| EP-2189443-B1 | TRICYCLIC AMIDE COMPOUND | RES FOUND ITSUU LAB (JP) | 2013-10-23 | — | — | EP | claimed |
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | claimed |
| US-20110152166-A1 | METHOD OF MODULATION OF PROTEIN PHOSPHORYLATION-DEPENDENT CONFORMATIONAL TRANSITIONS WITH LOW MOLECULAR WEIGHT COMPOUNDS | Biondi, Ricardo M. (DE) | 2011-06-23 | — | — | US | claimed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | claimed |
| US-20090312326-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2009-12-17 | — | — | US | claimed |
| US-7547718-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-16 | — | — | US | claimed |
| US-7544706-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-09 | — | — | US | claimed |
| EP-2057280-A2 | METHOD OF MODULATION OF PROTEIN PHOSPHORYLATION-DEPENDENT CONFORMATIONAL TRANSITIONS WITH LOW MOLECULAR WEIGHT COMPOUNDS | Biondi, Ricardo, Miguel (DE) | 2009-05-13 | — | — | EP | claimed |
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-29 | — | — | US | claimed |
| US-5589594-A | AMIDATION OF 7-AMINOCEPH-3-EM-4-CARBOXYLIC ESTER USING AMINOTHIAZOLE OXIME CARBOXYLIC ACID WITH REMOVAL OF PROTECTING GROUP BY ACID HYDROLYSIS AND CLEAVAGE OF DISULFIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-31 | — | — | US | claimed |
| US-5389625-A | Sweet taste; oral administering | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | claimed |
| EP-0555769-A2 | Process for the preparation of Cephem-Prodrug-esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-18 | — | — | EP | claimed |
| EP-0497978-A1 | CEPHALOSPORIN COMPOUNDS AND PRODUCTION THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1992-08-12 | — | — | EP | claimed |
| US-5036063-A | Penem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-30 | — | — | US | claimed |
| EP-0373388-A2 | Penem derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | claimed |
| EP-0307872-A2 | Esters of amino-acids, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | claimed |
| US-4446317-A | CEFUROXIME ESTERS | GLAXO OPERATIONS U.K. LIMITED (GB) | 1984-05-01 | — | — | US | claimed |
| US-4420478-A | ANTIBIOTICS, BACTERICIDES, CEPHALOSPORINS | ROUSSEL UCLAF (FR) | 1983-12-13 | — | — | US | claimed |
| US-4287193-A | ANTIBIOTIC DERIVATIVES OF CEPHALOSPORANIC ACID | ROUSSEL UCLAF (FR) | 1981-09-01 | — | — | US | claimed |