Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27925365 | 1.00 | HSD17B10 (0.46) | HSD17B10TSHRCA2CA1ESR2 | |
| SCHEMBL30988470 | 0.83 | HSD17B10 (0.46) | HSD17B10TSHRCA2CA1ESR2 | |
| SCHEMBL2087980 | 0.83 | HSP90AA1 (0.48) | HSD17B10TSHRHSP90AA1ALDH1A1CYP3A4 | |
| SCHEMBL28006279 | 0.81 | HSP90AA1 (0.47) | HSD17B10TSHRHSP90AA1ALDH1A1CYP3A4 | |
| SCHEMBL25356026 | 0.80 | APP (0.40) | HSD17B10CA2CA1HPGDALDH1A1 | |
| SCHEMBL258619 | 0.78 | HSP90AA1 (0.57) | HSD17B10TSHRCA2CA1ESR2 | |
| SCHEMBL740211 | 0.78 | SOS1 (0.44) | HSD17B10ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL30506427 | 0.78 | SOS1 (0.44) | HSD17B10ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29107394 | 0.75 | ESR1 (0.40) | HSD17B10ESR2ESR1HSD17B1HSD17B2 | |
| SCHEMBL28234038 | 0.75 | TP53 (0.46) | HSD17B10ESR2ESR1HSP90AA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600801-A | HSD17B13 inhibitors and uses thereof | FL2022-001公司 | 2023-08-15 | — | — | CN | disclosed |