SCHEMBL258619

SCHEMBL258619

Oc1ccc(Oc2ccc(O)c(Cl)c2)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.57
TSHR P16473 2/20 0.54
HSD17B10 Q99714 2/20 0.54
CA2 P00918 2/20 0.50
CA1 P00915 1/20 0.50
ESR2 Q92731 3/20 0.45
ESR1 P03372 2/20 0.45
KMO O15229 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SOS1 Q07889 1/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 1/20 0.40
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9445013 0.93 HSP90AA1 (0.68) HSP90AA1TSHRHSD17B10CA2CA1
SCHEMBL9623378 0.91 ESR1 (0.58) HSP90AA1TSHRHSD17B10CA2CA1
SCHEMBL11352238 0.91 HSP90AA1 (0.55) HSP90AA1TSHRHSD17B10CA2CA1
SCHEMBL11045939 0.91 HSP90AA1 (0.60) HSP90AA1TSHRHSD17B10CA2CA1
SCHEMBL23484455 0.89 HSP90AA1 (0.53) HSP90AA1TSHRHSD17B10CA2CA1
SCHEMBL7083294 0.89 LTA4H (0.54) HSP90AA1TSHRHSD17B10CA2CA1
SCHEMBL13048707 0.88 HSP90AA1 (0.47) HSP90AA1TSHRHSD17B10CA2CA1
SCHEMBL10704059 0.88 CA1 (0.61) HSP90AA1TSHRHSD17B10CA2CA1
SCHEMBL8652143 0.88 HSP90AA1 (0.47) HSP90AA1TSHRHSD17B10CA2CA1
SCHEMBL9445002 0.86 HSP90AA1 (0.50) HSP90AA1TSHRHSD17B10CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3235850-B1 POLYCARBONATE COPOLYMER AND PREPARATION METHOD THEREFOR SAMYANG CORP (KR) 2020-02-12 EP claimed
US-10081708-B2 Polycarbonate copolymer and preparation method therefor SAMYANG CORPORATION (KR) 2018-09-25 US claimed
US-20180162994-A1 Polycarbonate Copolymer And Preparation Method Therefor SAMYANG CORPORATION (KR) 2018-06-14 US claimed
EP-3235850-A1 POLYCARBONATE COPOLYMER AND PREPARATION METHOD THEREFOR Samyang Corporation (KR) 2017-10-25 EP claimed
EP-0738579-B1 Production method of polycarbonate MITSUBISHI GAS CHEMICAL CO (JP) 2003-10-29 EP claimed
US-6340738-B2 ESTER INTERCHANGE; CRYSTALLIZATION GENERAL ELECTRIC COMPANY 2002-01-22 US claimed
US-6294642-B1 TRANSESTERIFYING A DIHYDROXY COMPOUND AND CARBONIC DIESTER TO FORM THE POLYCARBONATE GENERAL ELECTRIC COMPANY 2001-09-25 US claimed
US-5777064-A TRANSESTERIFICATION; MELTING; KNEADING ACIDIC COMPOUND INTO MOLTEN POLYCARBONATE TO CONTINUOUSLY DEVOLATILIZE LOW MOLECULAR WEIGHT COMPOUNDS REMAINING IN POLYMER MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-07-07 US claimed
WO-1998017725-A1 1,4-CYCLOHEXANEDIMETHANOL BASED POLYESTER BLENDS EASTMAN CHEMICAL COMPANY (US) 1998-04-30 WO claimed
EP-0738579-A2 Production method of polycarbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1996-10-23 EP claimed
EP-0542256-B1 Polycarbonate resin solution for forming thermal-sublimating dye receiving layer film MITSUBISHI GAS CHEMICAL CO (JP) 1996-04-24 EP claimed
US-5447989-A Impact modifier is variation of core-shell polymer, shell is discontinuous ENICHEM S.P.A. (IT) 1995-09-05 US claimed
US-5427998-A Method for preparing a thermal transfer image-receiving sheet involving a polycarbonate dye-receiving layer MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 1995-06-27 US claimed
EP-0626425-A2 Compatible thermoplastic compositions based on polyesters and polycarbonates ENICHEM S.p.A. (IT) 1994-11-30 EP claimed
EP-0333002-B1 Heat-resistant resin composition IDEMITSU PETROCHEMICAL CO (JP) 1994-04-27 EP claimed
EP-0542256-A1 Polycarbonate resin solution for forming thermal-sublimating dye receiving layer film MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-05-19 EP claimed
EP-0333002-A2 Heat-resistant resin composition IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1989-09-20 EP claimed
US-4431767-A PARAFFINS AS RELEASE AGENTS; MOLDING MATERIALS RADIATIONS TRANSPARENT UNITIKA LTD. (JP) 1984-02-14 US claimed
US-4206100-A AROMATIC COPOLYESTER OF A BISPHENOL, POLYAMIDE, METAL OXIDE OR SALT ALKYLENE UNITIKA LTD. (JP) 1980-06-03 US claimed
US-4187358-A AROMATIC POLYESTER, ACYCLIC POLYAMIDE, IONOMER UNITIKA LTD. (JP) 1980-02-05 US claimed