Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25367415 | 1.00 | DGAT1 (0.36) | DGAT1F2RL1NPC1ALOX5APFEN1 | |
| SCHEMBL31411454 | 0.87 | DGAT1 (0.38) | DGAT1F2RL1NPC1ALOX5APFEN1 | |
| SCHEMBL31459865 | 0.85 | DGAT1 (0.36) | DGAT1F2RL1NPC1ALOX5APFEN1 | |
| SCHEMBL25366051 | 0.85 | DGAT1 (0.45) | DGAT1F2RL1NPC1ALOX5APFEN1 | |
| SCHEMBL29493833 | 0.85 | DGAT1 (0.45) | DGAT1F2RL1NPC1ALOX5APFEN1 | |
| SCHEMBL1955936 | 0.82 | DGAT1 (0.34) | DGAT1F2RL1NPC1ALOX5APFEN1 | |
| SCHEMBL29493774 | 0.79 | DGAT1 (0.37) | DGAT1F2RL1NPC1 | |
| SCHEMBL25365843 | 0.79 | DGAT1 (0.37) | DGAT1F2RL1NPC1 | |
| SCHEMBL25367779 | 0.79 | F2RL1 (0.36) | DGAT1F2RL1NPC1ALOX5APFEN1 | |
| SCHEMBL31411444 | 0.79 | DGAT1 (0.36) | DGAT1F2RL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600801-A | HSD17B13 inhibitors and uses thereof | FL2022-001公司 | 2023-08-15 | — | — | CN | disclosed |