Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.38 |
| ▸ | TDO2 | P48775 | 5/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.35 |
| ▸ | SETD2 | Q9BYW2 | 6/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544767 | 0.89 | PTPN11 (0.41) | IDO1TDO2HRH4EIF4A3SETD2 | |
| SCHEMBL30798890 | 0.79 | PTPN11 (0.36) | IDO1TDO2HRH4EIF4A3PLA2G7 | |
| SCHEMBL30798926 | 0.79 | IDO1 (0.38) | IDO1TDO2HRH4EIF4A3 | |
| SCHEMBL26312516 | 0.78 | IDO1 (0.41) | IDO1TDO2HRH4EIF4A3SETD2 | |
| SCHEMBL25427384 | 0.77 | CYP1A2 (0.44) | IDO1TDO2HRH4EIF4A3 | |
| SCHEMBL29655554 | 0.77 | CNR1 (0.46) | IDO1TDO2EIF4A3ALOX15 | |
| SCHEMBL29946325 | 0.76 | IDO1 (0.57) | IDO1TDO2EIF4A3ALOX15 | |
| SCHEMBL22395227 | 0.76 | IDO1 (0.57) | IDO1TDO2EIF4A3ALOX15 | |
| SCHEMBL30067353 | 0.74 | IDO1 (0.41) | IDO1TDO2HRH4EIF4A3 | |
| SCHEMBL30544758 | 0.74 | IDO1 (0.41) | IDO1TDO2HRH4EIF4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118986968-A | Pharmaceutical composition of 3CL inhibitor compound and application thereof | 深圳信立泰药业股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118165069-A | Nitrogen-containing spiro indoline compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-118146228-A | Deuterated spiro compound crystal form and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2024017270-A1 | SPIRO COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳信立泰药业股份有限公司 | 2024-01-25 | — | — | WO | disclosed |
| CN-116621917-A | Difluoro indole-spiro compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-08-22 | — | — | CN | disclosed |