SCHEMBL30537869

SCHEMBL30537869

CNC(=O)c1ccc(-c2cn3c(n2)sc2cc(Cl)ncc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.50
▸ RXFP1 Q9HBX9 2/20 0.50
▸ TP53 P04637 4/20 0.48
▸ MAPT P10636 2/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ THRB P10828 3/20 0.46
▸ POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24619245 1.00 LMNA (0.50) LMNARXFP1TP53MAPTSMN1; SMN2
SCHEMBL24740908 0.87 MAPT (0.52) LMNARXFP1TP53MAPTSMN1; SMN2
SCHEMBL30537902 0.87 MAPT (0.48) LMNARXFP1TP53MAPTSMN1; SMN2
SCHEMBL24619248 0.87 MAPT (0.48) LMNARXFP1TP53MAPTSMN1; SMN2
SCHEMBL24741290 0.84 LMNA (0.67) LMNARXFP1TP53MAPTTHRB
SCHEMBL29924748 0.81 LMNA (0.60) LMNARXFP1TP53MAPTTHRB
SCHEMBL24619415 0.81 LMNA (0.60) LMNARXFP1TP53MAPTTHRB
SCHEMBL30537887 0.81 THRB (0.39) LMNARXFP1TP53MAPTSMN1; SMN2
SCHEMBL24741270 0.81 LMNA (0.57) LMNARXFP1TP53MAPTTHRB
SCHEMBL24741800 0.81 LMNA (0.59) LMNARXFP1TP53MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116635028-A Modulators of c-MYC mRNA translation and their use in the treatment of cancer 艾尼莫生物科技公司 2023-08-22 — — CN disclosed
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