Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619499 | 0.97 | LMNA (0.68) | LMNAMAPTTP53THRBRXFP1 | |
| SCHEMBL24619490 | 0.92 | LMNA (0.65) | LMNAMAPTTP53THRBRXFP1 | |
| SCHEMBL24619496 | 0.92 | LMNA (0.65) | LMNAMAPTTP53THRBRXFP1 | |
| SCHEMBL24619493 | 0.87 | LMNA (0.79) | LMNAMAPTTP53THRBRXFP1 | |
| SCHEMBL24619447 | 0.87 | LMNA (0.70) | LMNAMAPTTP53THRBRXFP1 | |
| Formic Acid SCHEMBL29924663 | 0.86 | LMNA (0.57) | LMNAMAPTTP53THRBRXFP1 | |
| Formic Acid SCHEMBL29924676 | 0.86 | LMNA (0.64) | LMNAMAPTTP53THRBRXFP1 | |
| Formic Acid SCHEMBL29925352 | 0.85 | LMNA (0.63) | LMNAMAPTTP53THRBRXFP1 | |
| Formic Acid SCHEMBL29924881 | 0.85 | LMNA (0.63) | LMNAMAPTTP53THRBRXFP1 | |
| Formic Acid SCHEMBL29925161 | 0.85 | LMNA (0.58) | LMNAMAPTTP53THRBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635028-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2023-08-22 | — | — | CN | disclosed |