Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25348292 | 1.00 | LMNA (0.41) | LMNASMN1; SMN2RXFP1SORT1KDM4E | |
| SCHEMBL25346496 | 0.83 | NAPRT (0.41) | KDM4EALDH1A1HPGDAHRMEN1 | |
| SCHEMBL25349246 | 0.82 | KDM4E (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL20504453 | 0.81 | MCL1 (0.45) | LMNASMN1; SMN2RXFP1KDM4EALDH1A1 | |
| SCHEMBL30539556 | 0.73 | AKR1B1 (0.48) | L3MBTL1CNR2 | |
| SCHEMBL25366960 | 0.73 | KDM4E (0.40) | LMNASMN1; SMN2SORT1KDM4EALDH1A1 | |
| SCHEMBL29523230 | 0.73 | KDM4E (0.40) | LMNASMN1; SMN2SORT1KDM4EALDH1A1 | |
| SCHEMBL22902442 | 0.72 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2RXFP1SORT1KDM4E | |
| SCHEMBL2478685 | 0.72 | RXFP1 (0.37) | LMNARXFP1KDM4EMEN1KMT2A | |
| SCHEMBL20504325 | 0.71 | L3MBTL1 (0.47) | SMN1; SMN2KDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479388-A1 | ANTIVIRAL NAPHTHYRIDINONE COMPOUNDS | Gilead Sciences, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023154905-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-08-17 | — | — | WO | disclosed |