Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26635196 | 1.00 | XDH (0.49) | XDHERN1TDP1ROS1ALDH1A1 | |
| SCHEMBL30540241 | 0.87 | XDH (0.51) | XDHERN1TDP1ALDH1A1SRC | |
| SCHEMBL26635340 | 0.87 | XDH (0.51) | XDHERN1TDP1ALDH1A1SRC | |
| SCHEMBL26635302 | 0.84 | XDH (0.49) | XDHERN1TDP1ALDH1A1MAPT | |
| SCHEMBL30540281 | 0.84 | XDH (0.49) | XDHERN1TDP1ALDH1A1MAPT | |
| SCHEMBL26635441 | 0.83 | XDH (0.46) | XDHERN1TDP1ALDH1A1CYP1A2 | |
| SCHEMBL30540272 | 0.83 | XDH (0.46) | XDHERN1TDP1ALDH1A1CYP1A2 | |
| SCHEMBL26635453 | 0.82 | XDH (0.45) | XDHERN1TDP1HPGDMAPT | |
| SCHEMBL30540244 | 0.80 | XDH (0.46) | XDHERN1TDP1ALDH1A1MAPT | |
| SCHEMBL26635161 | 0.80 | XDH (0.46) | XDHERN1TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621778-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |