Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438289 | 1.00 | ERN1 (0.54) | ERN1PRMT6KCNH2TRIM24TRIM33 | |
| SCHEMBL5852 | 0.82 | HDAC2 (0.56) | ERN1KCNH2HDAC2DPP4CYP2E1 | |
| SCHEMBL8572231 | 0.81 | PRMT6 (0.46) | ERN1PRMT6KCNH2HDAC2CYP2E1 | |
| SCHEMBL13029661 | 0.81 | HDAC2 (0.54) | ERN1KCNH2HDAC2DPP4CYP2E1 | |
| SCHEMBL1334921 | 0.80 | KCNH2 (0.59) | ERN1PRMT6KCNH2CYP2E1CYP3A4 | |
| SCHEMBL31623345 | 0.77 | CYP2E1 (0.51) | ERN1KCNH2HDAC2DPP4CYP2E1 | |
| SCHEMBL4133624 | 0.77 | CYP2E1 (0.51) | ERN1KCNH2HDAC2DPP4CYP2E1 | |
| SCHEMBL9456798 | 0.77 | ERN1 (0.47) | ERN1KCNH2HDAC2DPP4CYP2E1 | |
| SCHEMBL346974 | 0.77 | TRIM24 (0.64) | TRIM24TRIM33CA12CA1CA2 | |
| SCHEMBL18002204 | 0.77 | ERN1 (0.53) | ERN1KCNH2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914242-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-07-25 | — | — | CN | disclosed |