Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | ERN1 | O75460 | 4/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13029661 | 0.98 | HDAC2 (0.54) | HDAC2ERN1GSK3BLTA4HCYP17A1 | |
| SCHEMBL29898509 | 0.89 | HDAC2 (0.48) | HDAC2ERN1GSK3BLTA4HCYP17A1 | |
| SCHEMBL28402564 | 0.89 | HDAC2 (0.51) | HDAC2ERN1GSK3BLTA4HCYP17A1 | |
| SCHEMBL12984926 | 0.89 | HDAC2 (0.48) | HDAC2ERN1GSK3BLTA4HCYP17A1 | |
| SCHEMBL29898510 | 0.89 | HDAC2 (0.48) | HDAC2ERN1GSK3BLTA4HCYP17A1 | |
| SCHEMBL13790222 | 0.83 | HDAC2 (0.64) | HDAC2ERN1GSK3BLTA4HCYP17A1 | |
| SCHEMBL3438289 | 0.82 | ERN1 (0.54) | HDAC2ERN1LTA4HCYP17A1CYP11B1 | |
| SCHEMBL30541237 | 0.82 | ERN1 (0.54) | HDAC2ERN1LTA4HCYP17A1CYP11B1 | |
| SCHEMBL338810 | 0.82 | LTA4H (0.70) | HDAC2ERN1GSK3BLTA4HCYP17A1 | |
| SCHEMBL6874614 | 0.81 | HDAC2 (0.58) | HDAC2ERN1GSK3BLTA4HCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116545-A | Erasable fluorescent material unlocked based on external stimulus | 太原理工大学 | 2020-05-08 | — | — | CN | claimed |
| US-9539336-B2 | Sialic acid derivatives | BROSSMER REINHARD (DE) | 2017-01-10 | — | — | US | claimed |
| EP-2863925-B1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2016-09-14 | — | — | EP | claimed |
| CN-103221436-B | The approach of polyacrylic ester | COLOPLAST A/S (DK) | 2015-09-09 | — | — | CN | claimed |
| US-20150174262-A1 | Sialic Acid Derivatives | BROSSMER REINHARD (DE) | 2015-06-25 | — | — | US | claimed |
| CN-103201295-B | Novel polymeric photoinitiators | COLOPLAST AS | 2015-04-29 | — | — | CN | claimed |
| CN-103906750-A | Novel chiral N-acyl-5, 6,7, (8-substituted) -tetrahydro- [1,2,4] triazolo [4,3-a ] pyrazines as selective NK-3 receptor antagonists, pharmaceutical compositions, methods for use in NK-3 receptor mediated diseases and chiral synthesis thereof | EUROSCREEN SA | 2014-07-02 | — | — | CN | claimed |
| CN-103221436-A | New routes to polyacrylates | COLOPLAST AS | 2013-07-24 | — | — | CN | claimed |
| CN-103201295-A | Novel polymeric photoinitiators | COLOPLAST AS | 2013-07-10 | — | — | CN | claimed |
| CN-102906093-A | Novel nk-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in nk-3 receptors mediated disorders | EUROSCREEN SA | 2013-01-30 | — | — | CN | claimed |
| CN-100343256-C | Biaryl substituted diazabicycloalkane amides as nicotinic acetylcholine agonists | ASTRAZENECA AB (SE) | 2007-10-17 | — | — | CN | claimed |
| CN-1678615-A | Biaryl substituted diazabicycloalkanes as nicotinic acetylcholine antagonists | ASTRAZENECA AB (SE) | 2005-10-05 | — | — | CN | claimed |
| US-4582903-A | Synthesis of unsaturated hydantoins with an inexpensive catalyst | STAUFFER CHEMICAL COMPANY (US) | 1986-04-15 | — | — | US | claimed |
| US-4345072-A | Process for the production of 5-arylidene hydantoins (B) | DEGUSSA AG (DE) | 1982-08-17 | — | — | US | claimed |
| CN-115515685-B | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2025-04-08 | — | — | CN | disclosed |
| US-12157731-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2024-12-03 | — | — | US | disclosed |
| US-12006376-B2 | Regioselectively substituted cellulose esters and films made therefrom | EASTMAN CHEMICAL COMPANY (US) | 2024-06-11 | — | — | US | disclosed |
| EP-0177072-A2 | Preparation of amino acids from unsaturated hydantoins | STAUFFER CHEMICAL COMPANY (US) | 1986-04-09 | — | — | EP | disclosed |
| US-4345072-A | Process for the production of 5-arylidene hydantoins (B) | DEGUSSA AG (DE) | 1982-08-17 | — | — | US | disclosed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12157731-B2 | EIF4E inhibitors and uses thereof | EIF4E, EIF4EBP1, EIF4A1 | HDAC2 1558/4885ERN1 76/4885GSK3B 1092/4885 |
| US-20150174262-A1 | Sialic Acid Derivatives | NEU1, SIGLEC9, SIGLEC7 | HDAC2 2298/4885ERN1 1413/4885GSK3B 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.