Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28372856 | 1.00 | IRAK4 (0.44) | IRAK4ALDH1A1HTTKDM4ERAB9A | |
| SCHEMBL25815819 | 0.82 | NLRP3 (0.36) | IRAK4ALDH1A1HTTKDM4ERAB9A | |
| SCHEMBL20545990 | 0.82 | IRAK4 (0.52) | IRAK4RAB9AMAPTSMN1; SMN2PARP1 | |
| SCHEMBL20545988 | 0.82 | IRAK4 (0.52) | IRAK4RAB9AMAPTSMN1; SMN2PARP1 | |
| SCHEMBL16768768 | 0.77 | RAB9A (0.50) | IRAK4ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL1077616 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1HTTKDM4ERAB9AHPGD | |
| SCHEMBL1051991 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1HTTKDM4ERAB9AHPGD | |
| SCHEMBL28369440 | 0.76 | MAPT (0.41) | ALDH1A1HTTKDM4ERAB9AHPGD | |
| Hydrochloric Acid SCHEMBL7321879 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1HTTKDM4ERAB9AHPGD | |
| Hydrochloric Acid SCHEMBL5742023 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1HTTKDM4ERAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615514-B1 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS INC (US) | 2023-11-22 | — | — | EP | disclosed |
| CN-110914242-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-07-25 | — | — | CN | disclosed |