Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14795060 | 0.92 | KMT2A (0.39) | KMT2AALOX15BLMPMP22GPR84 | |
| SCHEMBL28974981 | 0.90 | GPR84 (0.40) | KMT2AALOX15BLMPMP22GPR84 | |
| SCHEMBL14795059 | 0.90 | GPR84 (0.40) | KMT2AALOX15BLMPMP22GPR84 | |
| SCHEMBL2557470 | 0.90 | GPR84 (0.40) | KMT2AALOX15BLMPMP22GPR84 | |
| SCHEMBL403629 | 0.86 | ALOX15 (0.48) | KMT2AALOX15BLMPMP22TET2 | |
| SCHEMBL10975264 | 0.83 | GPR84 (0.46) | GPR84CA1CA2FFAR1ALDH1A1 | |
| SCHEMBL10799375 | 0.83 | GPR84 (0.46) | GPR84CA1CA2FFAR1ALDH1A1 | |
| SCHEMBL18342656 | 0.79 | — | — | |
| SCHEMBL22081794 | 0.79 | — | — | |
| SCHEMBL29101172 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789560-B | Method for synthesizing adipoyl amine and adipoyl nitrile by using 2-hydroxy adipoyl amine as raw material through dehydroxylation method | 河北工业大学 | 2025-05-30 | — | — | CN | claimed |
| CN-115286583-B | Diphenylamino pyrimidine-containing compound, preparation and application thereof as HDACs enzyme inhibitor | 山东大学 | 2024-01-30 | — | — | CN | claimed |
| CN-115043796-B | Method for preparing tetrahydrofuran dicarboxamide and 2-hydroxy adipamide through hydrogenation of furan dicarboxamide | 河北工业大学 | 2023-12-01 | — | — | CN | claimed |
| CN-116789560-A | Method for synthesizing adipoyl amine and adipoyl nitrile by using 2-hydroxy adipoyl amine as raw material through dehydroxylation method | 河北工业大学 | 2023-09-22 | — | — | CN | claimed |
| CN-115521228-B | BChE and HDAC double-target inhibitor and preparation method and application thereof | 中国药科大学 | 2023-08-22 | — | — | CN | claimed |
| CN-115521228-A | BChE and HDAC double-target inhibitor and preparation method and application thereof | 中国药科大学 | 2022-12-27 | — | — | CN | claimed |
| CN-115286583-A | Diphenylaminopyrimidine-containing compound, preparation and application thereof as HDACs enzyme inhibitor | 山东大学 | 2022-11-04 | — | — | CN | claimed |
| CN-115043796-A | Method for preparing tetrahydrofuran diformamide and 2-hydroxyadipamide by hydrogenation of furan diformamide | 河北工业大学 | 2022-09-13 | — | — | CN | claimed |
| CN-104592114-A | Quinolone substituted histone deacetylase inhibitor, preparation method and application thereof | UNIV SHANDONG | 2015-05-06 | — | — | CN | claimed |
| CN-116789560-B | Method for synthesizing adipoyl amine and adipoyl nitrile by using 2-hydroxy adipoyl amine as raw material through dehydroxylation method | 河北工业大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-116789560-B | Method for synthesizing adipoyl amine and adipoyl nitrile by using 2-hydroxy adipoyl amine as raw material through dehydroxylation method | 河北工业大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-115286583-B | Diphenylamino pyrimidine-containing compound, preparation and application thereof as HDACs enzyme inhibitor | 山东大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115043796-B | Method for preparing tetrahydrofuran dicarboxamide and 2-hydroxy adipamide through hydrogenation of furan dicarboxamide | 河北工业大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-115043796-B | Method for preparing tetrahydrofuran dicarboxamide and 2-hydroxy adipamide through hydrogenation of furan dicarboxamide | 河北工业大学 | 2023-12-01 | — | — | CN | disclosed |
| WO-2009035718-A1 | TARTRATE SALTS OR COMPLEXES OF QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009026446-A2 | HDAC INHIBITORS | ARQULE, INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| WO-2008033747-A9 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS INC (MA) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008033749-A2 | QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008033747-A2 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008033744-A2 | DNA METHYL TRANSFERASE INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |