Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 3/20 | 0.57 |
| ▸ | AXL | P30530 | 2/20 | 0.57 |
| ▸ | ULK1 | O75385 | 6/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467223 | 1.00 | PRKCI (0.57) | PRKCIAXLULK1JAK1AURKA | |
| SCHEMBL10201641 | 0.83 | PRKCI (0.62) | PRKCIAXLJAK1AURKAJAK2 | |
| SCHEMBL18012903 | 0.83 | PRKCI (0.49) | PRKCIAXLULK1JAK1AURKA | |
| SCHEMBL21855819 | 0.79 | PRKCI (0.41) | PRKCIAXLULK1JAK1AURKA | |
| SCHEMBL21893423 | 0.79 | ULK1 (0.47) | PRKCIAXLULK1JAK1AURKA | |
| SCHEMBL20243873 | 0.78 | PRKCI (0.55) | PRKCIAXLJAK1JAK2KDR | |
| SCHEMBL24656163 | 0.77 | PRKCI (0.42) | PRKCIAXLULK1JAK1AURKA | |
| SCHEMBL29431105 | 0.77 | PRKCI (0.62) | PRKCIAXLAURKAJAK2KDR | |
| SCHEMBL1749025 | 0.77 | PRKCI (0.62) | PRKCIAXLAURKAJAK2KDR | |
| SCHEMBL1356886 | 0.76 | PRKCI (0.67) | PRKCIAXLJAK1AURKAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341124-B | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2024-09-20 | — | — | CN | disclosed |
| EP-4214199-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |