Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 5/20 | 0.47 |
| ▸ | PRKCI | P41743 | 3/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.38 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21855819 | 0.79 | PRKCI (0.41) | ULK1PRKCIAXLJAK1JAK2 | |
| SCHEMBL1467223 | 0.79 | PRKCI (0.57) | ULK1PRKCIAXLJAK1JAK2 | |
| SCHEMBL18012903 | 0.79 | PRKCI (0.49) | ULK1PRKCIAXLJAK1JAK2 | |
| SCHEMBL30543159 | 0.79 | PRKCI (0.57) | ULK1PRKCIAXLJAK1JAK2 | |
| SCHEMBL24656163 | 0.77 | PRKCI (0.42) | ULK1PRKCIAXLJAK1JAK2 | |
| SCHEMBL24348505 | 0.77 | NUDT1 (0.47) | PRKCIAXLJAK2AURKAKDR | |
| SCHEMBL22941208 | 0.76 | PRKCI (0.47) | PRKCIAXLJAK2AURKAKDR | |
| SCHEMBL15331134 | 0.76 | ULK1 (0.39) | ULK1PRKCIAXLJAK1JAK2 | |
| SCHEMBL20371789 | 0.76 | PRKCI (0.45) | ULK1PRKCIAXLJAK1JAK2 | |
| SCHEMBL21677833 | 0.76 | BRD4 (0.43) | ULK1PRKCIAXLJAK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |