Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25367275 | 1.00 | TAAR1 (0.32) | TAAR1SNCALPLLIPGHTR7 | |
| SCHEMBL2524790 | 0.85 | TAAR1 (0.39) | TAAR1SNCALPLLIPG | |
| SCHEMBL26062457 | 0.78 | TAAR1 (0.30) | TAAR1 | |
| SCHEMBL31405030 | 0.78 | EGFR (0.35) | TAAR1SNCALPLLIPG | |
| SCHEMBL17258925 | 0.73 | EGFR (0.35) | HTR2B | |
| SCHEMBL21296157 | 0.73 | LPL (0.37) | LPLLIPG | |
| SCHEMBL12078593 | 0.71 | PARP10 (0.36) | — | |
| SCHEMBL12078361 | 0.70 | FFAR4 (0.37) | — | |
| SCHEMBL25368043 | 0.70 | TAAR1 (0.38) | TAAR1 | |
| SCHEMBL5899744 | 0.70 | CA1 (0.38) | SNCALPLLIPGHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479045-A2 | INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023159148-A2 | INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |