Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | CPS1 | P31327 | 4/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552502 | 0.78 | ALDH1A1 (0.50) | TAAR1ALDH1A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL5775046 | 0.75 | TRPV4 (0.35) | TAAR1ALDH1A1CYP1A2FFAR1 | |
| SCHEMBL8098541 | 0.74 | FFAR1 (0.46) | PTGDR2FFAR1 | |
| SCHEMBL25368036 | 0.72 | KDM1A (0.33) | TAAR1KDM1A | |
| SCHEMBL1042615 | 0.71 | TAAR1 (0.44) | TAAR1ALDH1A1MAOAMAOBCYP1A1 | |
| SCHEMBL30083748 | 0.71 | TAAR1 (0.44) | TAAR1ALDH1A1MAOAMAOBCYP1A1 | |
| SCHEMBL898637 | 0.70 | PTGDR2 (0.42) | PTGDR2 | |
| SCHEMBL25367275 | 0.70 | TAAR1 (0.32) | TAAR1 | |
| SCHEMBL30543727 | 0.70 | TAAR1 (0.32) | TAAR1 | |
| SCHEMBL27779814 | 0.70 | HTR1A (0.36) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212699-A | NLRP3 inhibitors | PTC医疗公司 | 2024-12-27 | — | — | CN | disclosed |
| EP-4479045-A2 | INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023159148-A2 | INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023159148-A2 | INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |