Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246435 | 0.73 | PIM1 (0.44) | PIM1PIM2PARP1SMN1; SMN2LMNA | |
| SCHEMBL4110397 | 0.72 | MAPKAPK2 (0.64) | PIM1PIM2ALDH1A1AURKAJAK2 | |
| SCHEMBL25194691 | 0.71 | SMN1; SMN2 (0.48) | PIM1PARP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7046486 | 0.71 | SMN1; SMN2 (0.58) | PIM1PARP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL18342008 | 0.68 | MAPKAPK2 (0.76) | PIM1PIM2PARP1ADORA2AGSK3A | |
| SCHEMBL9321123 | 0.68 | IP6K1 (0.59) | PIM1PIM2PARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9541195 | 0.67 | PARP1 (0.62) | PIM1PARP1ALDH1A1SMN1; SMN2AURKA | |
| SCHEMBL15618278 | 0.65 | AURKA (0.41) | ALDH1A1LMNAAURKADYRK1ACHEK1 | |
| SCHEMBL1738597 | 0.65 | SMN1; SMN2 (0.52) | PIM1PARP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1921269 | 0.65 | ACHE (0.44) | PARP1ALDH1A1SMN1; SMN2ADORA2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118946566-A | Heterocyclic compounds as ubiquitin-specific protease 7 inhibitors | 阿尔麦克探索有限公司 | 2024-11-12 | — | — | CN | claimed |
| EP-4466072-A1 | HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS | Almac Discovery Limited (GB) | 2024-11-27 | — | — | EP | disclosed |
| CN-118946566-A | Heterocyclic compounds as ubiquitin-specific protease 7 inhibitors | 阿尔麦克探索有限公司 | 2024-11-12 | — | — | CN | disclosed |
| WO-2023139241-A1 | HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS | ALMAC DISCOVERY LIMITED (GB) | 2023-07-27 | — | — | WO | disclosed |