Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 10/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581682 | 0.75 | ACHE (0.39) | SMN1; SMN2LMNATSHRADORA2ASLC6A4 | |
| Allopurinol SCHEMBL4628 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNATSHRADORA2ASLC6A4 | |
| Allopurinol SCHEMBL29793328 | 0.72 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNATSHRADORA2ASLC6A4 | |
| Allopurinol SCHEMBL7202471 | 0.72 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNATSHRADORA2ASLC6A4 | |
| Allopurinol SCHEMBL137085 | 0.72 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNATSHRADORA2ASLC6A4 | |
| SCHEMBL25194691 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNATSHRADORA2ASLC6A4 | |
| Allopurinol SCHEMBL2565656 | 0.72 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNATSHRADORA2ASLC6A4 | |
| Allopurinol SCHEMBL6142914 | 0.72 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNATSHRADORA2ASLC6A4 | |
| SCHEMBL7487801 | 0.72 | ABL1 (0.55) | SMN1; SMN2LMNATSHRADORA2ASLC6A4 | |
| SCHEMBL30545367 | 0.71 | PIM1 (0.48) | SMN1; SMN2LMNATSHRADORA2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012075562-A1 | MICROSPORE TRANSFORMATION METHODOLOGY BY MACROINJECTION | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2012-06-14 | — | — | WO | disclosed |
| US-6696565-B2 | SELF-ASSEMBLING; PHYSICAL PROPERTIES; THERMOCONDUCTIVITY | PURDUE RESEARCH FOUNDATION | 2004-02-24 | — | — | US | disclosed |