SCHEMBL305456

SCHEMBL305456

CN(C)c1ccc(C=Cc2ccncc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 1.00
SMN1; SMN2 Q16637 4/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
CASP1 P29466 2/20 1.00
HBB P68871 2/20 1.00
NPC1 O15118 2/20 1.00
RAB9A P51151 2/20 1.00
ALOX15 P16050 1/20 1.00
RELA Q04206 1/20 0.63
CHRM5 P08912 1/20 0.62
CHKA P35790 1/20 0.62
APP P05067 5/20 0.61
GAA P10253 1/20 0.55
BRCA1 P38398 1/20 0.55
CASP7 P55210 1/20 0.55
PTGS1 P23219 1/20 0.55
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
ALPG P10696 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL532373 1.00 MAPT (1.00) MAPTSMN1; SMN2MEN1KMT2ACASP1
Hydrochloric Acid SCHEMBL9803942 0.98 MAPT (0.96) MAPTSMN1; SMN2MEN1KMT2ACASP1
Bromide SCHEMBL28824563 0.98 MAPT (0.96) MAPTSMN1; SMN2MEN1KMT2ACASP1
Hydrochloric Acid SCHEMBL9803944 0.98 MAPT (0.96) MAPTSMN1; SMN2MEN1KMT2ACASP1
Bromide SCHEMBL27884858 0.98 MAPT (0.96) MAPTSMN1; SMN2MEN1KMT2ACASP1
Bromide SCHEMBL27779245 0.98 MAPT (0.96) MAPTSMN1; SMN2MEN1KMT2ACASP1
SCHEMBL5887491 0.87 MAPT (0.77) MAPTSMN1; SMN2MEN1KMT2ACASP1
SCHEMBL3025040 0.86 RELA (0.81) MAPTSMN1; SMN2MEN1KMT2ACASP1
SCHEMBL13467434 0.86 RELA (0.81) MAPTSMN1; SMN2MEN1KMT2ACASP1
SCHEMBL1714446 0.86 RELA (0.81) MAPTSMN1; SMN2MEN1KMT2ACASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878852-A Metal organic framework-based porous liquid functional flame retardant and preparation method thereof 北京理工大学 2024-11-01 CN claimed
CN-111500249-A Low-dielectric-property low-water-absorption halogen-free copper-clad plate and preparation method thereof 山东金宝电子股份有限公司 2020-08-07 CN claimed
CN-104900410-B Phosphorus titanheteropolytungstate and the photoelectricity conversion thin film and its sensing property of hemicyanine dye hydridization 北京工商大学 2017-12-19 CN claimed
CN-105153018-B A kind of half cyanines derivative pH ratio fluorescent sensors 北京工商大学 2017-09-22 CN claimed
CN-104877667-B A kind of fluorescence response thin-film material with humidity sensitivity and preparation method thereof 北京师范大学 2016-08-17 CN claimed
CN-103943805-B Lithium rechargeable battery and barrier film thereof NINGDE AMPEREX TECHNOLOGY LTD. (CN) 2016-04-06 CN claimed
CN-105153018-A Hemicyanine derivative pH fluorescence ratio sensor UNIV BEIJING TECH & BUSINESS 2015-12-16 CN claimed
CN-104877667-A Fluorescent response thin-film material having humidity sensitive characteristics and preparation method thereof UNIV BEIJING NORMAL 2015-09-02 CN claimed
US-8861921-B2 Photovoltaic device with frequency conversion region WAKE FOREST UNIVERSITY (US) 2014-10-14 US claimed
CN-103943805-A Lithium ion secondary battery and diaphragm thereof NINGDE AMPEREX TECHNOLOGY LTD 2014-07-23 CN claimed
US-8050531-B2 Dendrimer based terahertz generator APPLIED RESEARCH AND PHOTONICS, INC. 2011-11-01 US claimed
US-7919755-B2 Dendrimer based electro-optic sensor APPLIED RESEARCH AND PHOTONICS, INC. 2011-04-05 US claimed
US-7854505-B2 Passive and active photonic crystal structures and devices THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2010-12-21 US claimed
WO-2010144438-A1 PHOTOVOLTAIC DEVICE WITH FREQUENCY CONVERSION REGION WAKE FOREST UNIVERSITY (US) 2010-12-16 WO claimed
US-20090323014-A1 PASSIVE AND ACTIVE PHOTONIC CRYSTAL STRUCTURES AND DEVICES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-31 US claimed
US-20080128618-A1 Dendrimer Based Electro-Optic Sensor APPLIED RESEARCH AND PHOTONICS, INC. 2008-06-05 US claimed
US-20080099698-A1 Dendrimer Based Terahertz Generator APPLIED RESEARCH AND PHOTONICS, INC. 2008-05-01 US claimed
US-6558736-B2 Vapor deposition in vacuum THE TRUSTEES OF PRINCETON UNIVERSITY 2003-05-06 US claimed
EP-0828867-B1 METHOD AND APPARATUS USING ORGANIC VAPOR PHASE DEPOSITION FOR THE GROWTH OF ORGANIC THIN FILMS WITH LARGE OPTICAL NON-LINEARITIES UNIV PRINCETON (US) 2003-01-08 EP claimed
US-20020155230-A1 Low pressure vapor phase deposition of organic thin films FORREST STEPHEN R (US) 2002-10-24 US claimed