Sugi Predict

Sugi Predict / Compounds / SCHEMBL30546034

SCHEMBL30546034

SCHEMBL30546034

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)CN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(N)=O

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ GRIN2D O15399 1/20 0.71
▸ GRIN3B O60391 1/20 0.71
▸ GRIN1 Q05586 1/20 0.71
▸ GRIN2A Q12879 1/20 0.71
▸ GRIN2B Q13224 1/20 0.71
▸ GRIN2C Q14957 1/20 0.71
▸ GRIN3A Q8TCU5 1/20 0.71
▸ TFPI P10646 1/20 0.56
▸ RXFP1 Q9HBX9 2/20 0.51
▸ PTH1R Q03431 3/20 0.50
▸ VIPR1 P32241 2/20 0.48
▸ KISS1R Q969F8 2/20 0.48
▸ HRAS P01112 1/20 0.48
▸ KRAS P01116 1/20 0.48
▸ SOS1 Q07889 1/20 0.48
▸ VIPR2 P41587 1/20 0.47
▸ TASP1 Q9H6P5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Conantokin G SCHEMBL29359804 0.98 GRIN2D (0.69) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Conantokin G SCHEMBL29405425 0.98 GRIN2D (0.69) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31202698 0.96 GRIN2D (0.66) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30463853 0.94 GRIN2D (0.64) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30296729 0.92 GRIN2D (0.61) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29489382 0.90 GRIN2D (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31578281 0.90 GRIN2D (0.57) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29489379 0.86 GRIN2D (0.55) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30176466 0.85 RXFP1 (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31019331 0.85 VIPR1 (0.53) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4475953-A1 NMDAR ANTAGONISTS PREVENT AGEING AND AGING-ASSOCIATED CONDITIONS AND DISEASES THROUGH INCREASING 20S PROTEASOME ACTIVITY SAHIN, Fikret (TR) 2024-12-18 — — EP claimed
WO-2023154014-A1 NMDAR ANTAGONISTS PREVENT AGEING AND AGING-ASSOCIATED CONDITIONS AND DISEASES THROUGH INCREASING 20S PROTEASOME ACTIVITY SAHIN FIKRET (TR) 2023-08-17 — — WO claimed
US-20250161238-A1 NMDAR Antagonists Prevent Ageing and Aging-Associated Conditions and Diseases Through Increasing 20S Proteasome Activity SAHIN FIKRET (TR) 2025-05-22 — — US disclosed
EP-4475953-A1 NMDAR ANTAGONISTS PREVENT AGEING AND AGING-ASSOCIATED CONDITIONS AND DISEASES THROUGH INCREASING 20S PROTEASOME ACTIVITY SAHIN, Fikret (TR) 2024-12-18 — — EP disclosed
WO-2023154014-A1 NMDAR ANTAGONISTS PREVENT AGEING AND AGING-ASSOCIATED CONDITIONS AND DISEASES THROUGH INCREASING 20S PROTEASOME ACTIVITY SAHIN FIKRET (TR) 2023-08-17 — — WO disclosed
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