Conantokin G

Conantokin G

SCHEMBL29405425

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C(=O)O)C(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C(=O)O)C(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C(=O)O)C(=O)O)NC(=O)[C@H](CC(C(=O)O)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)CN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C(=O)O)C(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(N)=O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GRIN2D O15399 1/20 0.69
▸ GRIN3B O60391 1/20 0.69
▸ GRIN1 Q05586 1/20 0.69
▸ GRIN2A Q12879 1/20 0.69
▸ GRIN2B Q13224 1/20 0.69
▸ GRIN2C Q14957 1/20 0.69
▸ GRIN3A Q8TCU5 1/20 0.69
▸ TFPI P10646 1/20 0.54
▸ RXFP1 Q9HBX9 2/20 0.50
▸ PTH1R Q03431 3/20 0.49
▸ VIPR1 P32241 3/20 0.48
▸ VIPR2 P41587 3/20 0.47
▸ HRAS P01112 1/20 0.47
▸ KRAS P01116 1/20 0.47
▸ SOS1 Q07889 1/20 0.47
▸ KISS1R Q969F8 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Conantokin G SCHEMBL29359804 1.00 GRIN2D (0.69) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30546034 0.98 GRIN2D (0.71) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31202698 0.95 GRIN2D (0.66) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30463853 0.94 GRIN2D (0.64) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30296729 0.92 GRIN2D (0.61) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29489382 0.90 GRIN2D (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31578281 0.89 GRIN2D (0.57) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29489379 0.86 GRIN2D (0.55) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30567452 0.85 TFPI (0.58) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30176466 0.85 RXFP1 (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117315455-B Remote sensing cloud detection method considering cloud information characterization index and geometric form characteristics 重庆市地理信息和遥感应用中心(重庆市测绘产品质量检验测试中心) 2024-11-08 — — CN claimed
WO-2024019378-A1 RECOMBINANT EXPRESSION VECTOR FOR CONANTOKIN-G SECRETION AND ATTENUATED SALMONELLA STRAIN TRANSFORMED THEREWITH 충남대학교 산학협력단 2024-01-25 — — WO claimed
CN-117315455-A Remote sensing cloud detection method considering cloud information characterization index and geometric form characteristics 重庆市地理信息和遥感应用中心(重庆市测绘产品质量检验测试中心) 2023-12-29 — — CN claimed
EP-4085066-A1 CONUS-BASED TOXIN PEPTIDES, NUCLEIC ACIDS ENCODING SAME AND USES THEREOF IN MODULATING NMDA RECEPTORS Technion Research & Development Foundation Limited (IL) 2022-11-09 — — EP claimed
US-20220324922-A1 CONUS-BASED TOXIN PEPTIDES, NUCLEIC ACIDS ENCODING SAME AND USES THEREOF IN MODULATING NMDA RECEPTORS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2022-10-13 — — US claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12622922-B2 Compositions and methods for metal containing formulations capable of modulating immune response THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-05-12 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-12583892-B2 Conus-based toxin peptides, nucleic acids encoding same and uses thereof in modulating NMDA receptors TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (IL) 2026-03-24 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-20250375388-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF BIOMACROMOLECULE AGENTS UNIV MICHIGAN REGENTS (US) 2025-12-11 — — US disclosed
US-20220175872-A1 THERMOGENIC COMPOSITIONS AND METHODS OHIO STATE INNOVATION FOUNDATION 2022-06-09 — — US disclosed
WO-2022115715-A1 COMPOSITIONS AND METHODS FOR SELECTIVE DEPLETION OF TARGET MOLECULES FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2022-06-02 — — WO disclosed
US-11331393-B2 Renal-homing peptide conjugates and methods of use thereof Blaze Bioscience, Inc. (US) 2022-05-17 — — US disclosed
WO-2022081993-A1 CRYSTALLINE POLYMORPHIC FORMS OF STING AGONISTS ASSOCIATED WITH METAL IONS CAPABLE OF MODULATING AN IMMUNE RESPONSE THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-04-21 — — WO disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
CN-114164867-A Steel structure foundation flashing structure and mounting method thereof 汉尔姆建筑科技有限公司 2022-03-11 — — CN disclosed
US-20220072023-A1 COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS GRIN2D 4/4885GRIN3B 27/4885GRIN1 8/4885
US-20220072023-A1 COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE MYD88, STING1, TLR3 GRIN2D 4060/4885GRIN3B 2120/4885GRIN1 2410/4885
US-12583892-B2 Conus-based toxin peptides, nucleic acids encoding same and uses thereof in modulating NMDA receptors GRIN1, GRIN3A, GRIN2B GRIN2D 14/4885GRIN3B 5/4885GRIN1 1/4885
US-11331393-B2 Renal-homing peptide conjugates and methods of use thereof CXCL12, ATP6V1B1, VIP GRIN2D 4516/4885GRIN3B 1861/4885GRIN1 3589/4885
US-20220175872-A1 THERMOGENIC COMPOSITIONS AND METHODS LRBA, IAPP, FABP4 GRIN2D 3418/4885GRIN3B 2995/4885GRIN1 3298/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 GRIN2D 2136/4885GRIN3B 1231/4885GRIN1 882/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 GRIN2D 2602/4885GRIN3B 2523/4885GRIN1 2588/4885
US-12622922-B2 Compositions and methods for metal containing formulations capable of modulating immune response STING1, CGAS, TLR3 GRIN2D 2107/4885GRIN3B 741/4885GRIN1 2095/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT GRIN2D 742/4885GRIN3B 464/4885GRIN1 305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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