Conantokin G

Conantokin G

SCHEMBL29359804

CCC(C)C(NC(=O)C(CC(C)C)NC(=O)C(CC(C(=O)O)C(=O)O)NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CC(C(=O)O)C(=O)O)NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C(=O)O)C(=O)O)NC(=O)C(CC(C(=O)O)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C(=O)O)C(=O)O)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(CC(N)=O)C(N)=O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GRIN2D O15399 1/20 0.69
▸ GRIN3B O60391 1/20 0.69
▸ GRIN1 Q05586 1/20 0.69
▸ GRIN2A Q12879 1/20 0.69
▸ GRIN2B Q13224 1/20 0.69
▸ GRIN2C Q14957 1/20 0.69
▸ GRIN3A Q8TCU5 1/20 0.69
▸ TFPI P10646 1/20 0.54
▸ RXFP1 Q9HBX9 2/20 0.50
▸ PTH1R Q03431 3/20 0.49
▸ VIPR1 P32241 3/20 0.48
▸ VIPR2 P41587 3/20 0.47
▸ HRAS P01112 1/20 0.47
▸ KRAS P01116 1/20 0.47
▸ SOS1 Q07889 1/20 0.47
▸ KISS1R Q969F8 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Conantokin G SCHEMBL29405425 1.00 GRIN2D (0.69) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30546034 0.98 GRIN2D (0.71) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31202698 0.95 GRIN2D (0.66) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30463853 0.94 GRIN2D (0.64) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30296729 0.92 GRIN2D (0.61) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29489382 0.90 GRIN2D (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31578281 0.89 GRIN2D (0.57) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29489379 0.86 GRIN2D (0.55) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30567452 0.85 TFPI (0.58) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30176466 0.85 RXFP1 (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264860-A2 METHODS OF TREATING POST-COVID AIRWAY DISEASE YALE UNIVERSITY (US) 2025-12-26 — — WO claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-20260062709-A1 METHODS FOR IMPROVING PRODUCTION OF BIOLOGICAL PRODUCTS BY REDUCING THE LEVEL OF ENDOGENOUS PROTEIN LONZA AG (CH) 2026-03-05 — — US disclosed
US-12534511-B2 Serum albumin-binding fibronectin type III domains BRISTOL-MYERS SQUIBB COMPANY (US) 2026-01-27 — — US disclosed
US-12529088-B2 Helper factors for expressing proteins in yeast LONZA LTD (CH) 2026-01-20 — — US disclosed
US-20260001873-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2026-01-01 — — US disclosed
WO-2025264860-A2 METHODS OF TREATING POST-COVID AIRWAY DISEASE YALE UNIVERSITY (US) 2025-12-26 — — WO disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed
CN-108218849-B Novel inhibitors 维沃永治疗公众有限公司 2022-03-01 — — CN disclosed
US-20220049275-A1 SSI CELLS WITH PREDICTABLE AND STABLE TRANSGENE EXPRESSION AND METHODS OF FORMATION LONZA AG (CH) 2022-02-17 — — US disclosed
US-20220042064-A1 CARBON-SOURCE REGULATED PROTEIN PRODUCTION IN A RECOMBINANT HOST CELL LONZA LTD (CH) 2022-02-10 — — US disclosed
EP-3947695-A1 MUT- METHYLOTROPHIC YEAST Universität für Bodenkultur Wien (AT) 2022-02-09 — — EP disclosed
CN-114026239-A MUT-methanol nutritional yeast 维也纳自然资源与生命科学大学 2022-02-08 — — CN disclosed
CN-114026213-A Continuous blade type impeller 龙沙有限公司 2022-02-08 — — CN disclosed
US-11236520-B2 Customizable facility LONZA LTD (CH) 2022-02-01 — — US disclosed
EP-3942014-A1 CONTINUOUS BLADE IMPELLER Lonza Ltd. (CH) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001873-A1 NOVEL INHIBITORS GLS, GLS2, SULT1E1 GRIN2D 244/4885GRIN3B 1148/4885GRIN1 157/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS GRIN2D 4/4885GRIN3B 27/4885GRIN1 8/4885
US-12534511-B2 Serum albumin-binding fibronectin type III domains FN1, ALB, FGB GRIN2D 4741/4885GRIN3B 4279/4885GRIN1 4544/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 GRIN2D 2136/4885GRIN3B 1231/4885GRIN1 882/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 GRIN2D 2602/4885GRIN3B 2523/4885GRIN1 2588/4885
US-20260062709-A1 METHODS FOR IMPROVING PRODUCTION OF BIOLOGICAL PRODUCTS BY REDUCING THE LEVEL OF ENDOGENOUS PROTEIN MRPL21, SET, RPS27A GRIN2D 4520/4885GRIN3B 4770/4885GRIN1 4872/4885
US-12529088-B2 Helper factors for expressing proteins in yeast UPF1, ILF3, YIF1A GRIN2D 4865/4885GRIN3B 4654/4885GRIN1 4710/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT GRIN2D 742/4885GRIN3B 464/4885GRIN1 305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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