SCHEMBL30546243

SCHEMBL30546243

O=C1OC(O)c2cc(Cl)ccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.41
AR P10275 1/20 0.38
CES1 P23141 1/20 0.38
PSMD14 O00487 1/20 0.38
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RET P07949 1/20 0.37
KDR P35968 1/20 0.37
PPOX P50336 1/20 0.37
HTR2B P41595 1/20 0.37
CACNB4 O00305 1/20 0.37
CACNA1A O00555 1/20 0.37
CACNA1G O43497 1/20 0.37
CACNG3 O60359 1/20 0.37
CACNA1F O60840 1/20 0.37
CACNA1H O95180 1/20 0.37
CACNB3 P54284 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87581 1.00 S100A4 (0.41) S100A4ARCES1PSMD14ALDH1A1
SCHEMBL9202229 0.85 AR (0.41) S100A4ARALDH1A1KDM4EGAA
SCHEMBL10508690 0.82 AHR (0.43) KDM4ERETKDRMAPT
SCHEMBL10508695 0.82 AHR (0.43) KDM4ERETKDRMAPT
SCHEMBL8376684 0.79 S100A4 (0.42) S100A4ARCES1PSMD14ALDH1A1
SCHEMBL25261284 0.78 TYMS (0.42) S100A4ARPSMD14ALDH1A1KDM4E
SCHEMBL18705382 0.78 S100A4 (0.41) S100A4ARALDH1A1KDM4EGAA
SCHEMBL2532868 0.78 S100A4 (0.41) S100A4ARALDH1A1KDM4EGAA
SCHEMBL3241979 0.78 ELANE (0.41) ALDH1A1KDM4EGAAMEN1KMT2A
SCHEMBL25312082 0.78 TYMS (0.42) S100A4ARPSMD14ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118373791-A Allyl phthalide compound and preparation method and application thereof 南京工业大学 2024-07-23 CN claimed
CN-118373791-A Allyl phthalide compound and preparation method and application thereof 南京工业大学 2024-07-23 CN disclosed
WO-2023192989-A2 PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS AZKARRA THERAPEUTICS, INC. (US) 2023-10-05 WO disclosed