Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18128865 | 0.85 | MAP2K4 (0.39) | MAP2K4L3MBTL1BCHEFAAHP2RX3 | |
| SCHEMBL16149702 | 0.85 | SCN9A (0.37) | MAP2K4TSHRBCHESSTR4FAAH | |
| SCHEMBL25292632 | 0.85 | STS (0.37) | MAP2K4TSHRBCHESSTR4FAAH | |
| SCHEMBL30548011 | 0.85 | STS (0.37) | MAP2K4TSHRBCHESSTR4FAAH | |
| SCHEMBL15719632 | 0.81 | TDP1 (0.36) | MAP2K4GAAMAPTTSHRL3MBTL1 | |
| SCHEMBL2674135 | 0.79 | MAP2K4 (0.44) | MAP2K4GAAL3MBTL1BCHEFAAH | |
| SCHEMBL25703825 | 0.76 | POLB (0.41) | ELANEGPR119 | |
| SCHEMBL25244706 | 0.74 | L3MBTL1 (0.43) | GAAMAPTTSHRL3MBTL1BCHE | |
| SCHEMBL8207359 | 0.73 | SCN9A (0.40) | MAP2K4L3MBTL1BCHESSTR4FAAH | |
| SCHEMBL25769987 | 0.73 | ELANE (0.40) | GAAMAPTTSHRL3MBTL1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447954-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | Icahn School of Medicine at Mount Sinai (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114472-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-06-22 | — | — | WO | disclosed |